4(1h)-pyridinone;4-PYRIDOL;4-oxo-1,4-dihydropyridine;4(1H)-PYRIDINONE;4HPY;4-PYRIDONE;4-PYRIDINONE;pyrid-4-one;4-PYRIDINOL;pyridin-4-one;Pyridin-4(1H)-one;4-(1H)-PYRIDONE;Hydroxypyridine,4;4(1H)-pyridone;G-PYRIDONE;1,4-DIHYDRO-4-PYRIDINONE FOR SYNTHESIS;4-(1H)-Pyridone;4-HDROXYPYRIDINE;4-(1H)-Pyridone, , pract;1,4-DIHYDRO-4-PYRIDINONE;
PSA
32.86000
LogP
0.37490
吡啶酮物化性质
外观与性状
米色粉末
折射率
1.513
闪点
107.8ºC
蒸汽压
0.265mmHg at 25°C
熔点
150-151 °C(lit.)
密度
1.111 g/cm3
沸点
230-235 °C12 mm Hg(lit.)
吡啶酮安全信息
WGK Germany
3
危险类别码
R36/37/38
安全说明
S26-S36
RTECS号
UU7701450
危险品标志
Xi
吡啶酮生产方法及用途
用途
用于合成利尿药物托拉塞米或其他药物中间体。
吡啶酮图谱
核磁图谱
吡啶酮合成路线
1.合成路线
77070-79-2
75%
108-96-3
Kharitonova; Panin; Belova
Russian Journal of Organic Chemistry, 2005 , vol. 41, # 8 p. 1113 - 1115
2.合成路线
119-61-9
3881-38-7
22%
108-96-3
1620-30-0
464-72-2
Journal of Heterocyclic Chemistry, , vol. 21, p. 1277 - 1280
3.合成路线
78526-39-3
108-96-3
13669-34-6
Sammes, Michael P.; Leung, Christopher W. F.; Mak, Chi Keung; Katritzky, Alan R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1585 - 1590