8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4-基]甲基]氨基]喹啉-3-甲腈

8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...基本信息

中文全称

8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4-基]甲基]氨基]喹啉-3-甲腈

中文别名

8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基-4-哌啶)-1H-1,2,3-三唑-4-基]甲基]氨基]-3-喹啉甲腈;

英文名称

8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-carbonitrile

英文别名

substituted 6-aminoquinoline-3-carbonitrile,34;8-CHLORO-4-[(3-CHLORO-4-FLUOROPHENYL)AMINO]-6-[[[1-(1-ETHYLPIPERIDIN-4-YL)-1H-1,2,3-TRIAZOL-4-YL]METHYL]AMINO]QUINOLINE-3-CARBONITRILE;Cot inhibitor-2;

PSA

94.69000

LogP

6.24028
8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...物化性质

折射率

1.702

闪点

385.2ºC

密度

1.45

沸点

713.3ºC at 760 mmHg
8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...图谱

核磁图谱

1H NMR : Predict

13C NMR : Predict
8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...合成路线

1.合成路线

915364-18-0

1175146-85-6

915363-56-3

参考文献

Wu, Junjun; Green, Neal; Hotchandani, Rajeev; Hu, Yonghan; Condon, Jeffrey; Huang, Adrian; Kaila, Neelu; Li, Huan-Qiu; Guler, Satenig; Li, Wei; Tam, Steve Y.; Wang, Qin; Pelker, Jeffrey; Marusic, Suzana; Hsu, Sang; Perry Hall; Telliez, Jean-Baptiste; Cui, Junqing; Lin, Lih-Ling Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 13 p. 3485 - 3488

2.合成路线

915364-18-0

1175146-85-6

915363-56-3

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 13 p. 3485 - 3488
8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...上下游产品

上游产品

915364-18-0
6-氨基-8-氯-4-[(3-氯-4-氟苯基)氨基]-3-喹啉甲腈

1175146-85-6
1-(1-乙基哌啶-4-基)三唑-4-甲醛

下游产品

915363-56-3
8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4-基]甲基]氨基]喹啉-3-甲腈

上游百科 1-(1-ethylpiperidin-4-yl)triazole-4-carbaldehyde

915363-56-3

8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...基本信息

8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...物化性质

8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...图谱

8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...合成路线

1.合成路线

915364-18-0

1175146-85-6

915363-56-3

2.合成路线

915364-18-0

1175146-85-6

915363-56-3

8-氯-4-[(3-氯-4-氟苯基)氨基]-6-[[[1-(1-乙基哌啶-4-基)-1H-1,2,3-三唑-4...上下游产品

上游产品

下游产品

上游百科