5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮

5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮基本信息

中文全称

5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮

中文别名

2H-环戊并[B]呋喃-2-酮,5-(苯甲酰氧基)六氢-4-[(1E)-3-氧代-1-辛烯-1-基]-,(3AR,4R,5R,6AS)-;地诺前列素中间体

英文名称

5-(benzoyloxy)-3,3a,4,5,6,6a-hexahydro-4-(3-oxo-1-octenyl)-2H-cyclopenta(b)furan-2-one

英文别名

(1S,5R,6R,7R)-2-oxa-6-[(E)-3-oxoocten-1-yl]-7-benzoyloxybicyclo[3.3.0]octan-3-one;(3aR,4R,5R,6aS)-2-oxo-4-((E)-3-oxooct-1-enyl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate;[3aR,4R(1E),5R,6aS]-5-benzoyloxy-4-(3-oxoocten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one;DN-BK;5-Benzoyloxy-3,3a,4,5,6,6a-hexahydro-4-(3-oxo-1-octenyl)-2H-cyclopenta[b]furan-2-one;(3aR,4R,5R,6aS)-4-((E)-3-oxo-1-octenyl)-2-oxo-5-phenylcarbonyloxyhexahydrocyclopenta[b]furan;(3aR,4R,5R,6aS)-benzoic acid 2-oxo-4-[(1E)-3-oxo-oct-1-enyl]-hexahydro-cyclopenta[b]furan-5-yl ester;Dinoprost intermediate

PSA

69.67000

LogP

3.86920
5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮物化性质

折射率

1.554

闪点

238.3ºC

密度

1.18g/cm3

沸点

546.8ºC at 760mmHg
5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮图谱

核磁图谱

Predict 1H proton NMR
5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮合成路线

1.合成路线

36969-89-8

39746-01-5

97%

49673-16-7

40834-86-4

参考文献

Kim, Seongjin; Bellone, Sophie; Maxey, Kirk M.; Powell, William S.; Lee, Gue-Jae; Rokach, Joshua Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 7 p. 1873 - 1876

2.合成路线

61728-15-2

39746-01-5

96%

40834-86-4

参考文献

Patel, Pranav; Lee, Gue-Jae; Kim, Seongjin; Grant, Gail E.; Powell, William S.; Rokach, Joshua Journal of Organic Chemistry, 2008 , vol. 73, # 18 p. 7213 - 7218

3.合成路线

36969-89-8

39746-01-5

89%

40834-86-4

参考文献

R-TECH UENO, LTD. Patent: US2007/244333 A1, 2007 ; Location in patent: Page/Page column 14-15 ;
5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮上下游产品

上游产品

36969-89-8
(2-氧代庚基)膦酸二甲酯

39746-01-5
[3aR(3aα,4α,5β,6aα)]-(-)-5-(苯甲酰氧基)六氢-2-氧代-2H-环戊并[b]呋喃-4-甲醛

61728-15-2

40834-86-4
5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮

下游产品

587869-81-6

40834-86-4
5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮

49673-16-7

上游百科 (2-氧代庚基)膦酸二甲酯 [3aR(3aα,4α,5β,6aα)]-(-)-5-(苯甲酰氧基)六氢-2-氧代-2H-环戊并[b]呋喃-4-甲醛
下游百科 [(3aR,4R,5R,6aS)-4-[(3S)-3-[tert-butyl(dimethyl)silyl]oxyoct-1-enyl]-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate

40834-86-4

5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮基本信息

5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮物化性质

5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮图谱

5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮合成路线

1.合成路线

36969-89-8

39746-01-5

49673-16-7

40834-86-4

2.合成路线

61728-15-2

39746-01-5

40834-86-4

3.合成路线

36969-89-8

39746-01-5

40834-86-4

5-苯甲酰氧基-3,3a,4,5,6,6a-六氢-4-(3-氧代-1-辛烯基)-2H-环戊并[b]呋喃-2-酮上下游产品

上游产品

下游产品

上游百科

下游百科