2-ethyl-5-(2-fluoropyridin-4-yl)-4-(3-methylphenyl)-1,3-thiazole - CAS号 365428-57-5 - 摩贝百科

: 2-ethyl-5-(2-fluoropyridin-4-yl)-4-(3-methylphenyl)-1,3-thiazole

CAS号：
365428-57-5

分子式：C17H15FN2S

2-ethyl-5-(2-fluoropyridin-4-yl)-4-(3-methylphenyl)-1,3-thiazole基本信息

中文全称

中文别名

英文名称

2-ethyl-5-(2-fluoropyridin-4-yl)-4-(3-methylphenyl)-1,3-thiazole

英文别名

2-ethyl-5-(2-fluoro-4-pyridyl)-4-(3-methylphenyl)-1,3-thiazole;2-ethyl-5-(2-fluoro-pyridin-4-yl)-4-(3-methylphenyl)-1,3-thiazole;

PSA

54.02000

LogP

4.88200
2-ethyl-5-(2-fluoropyridin-4-yl)-4-(3-methylphenyl)-1,3-thiazole图谱

核磁图谱

1H NMR : Predict

13C NMR : Predict
2-ethyl-5-(2-fluoropyridin-4-yl)-4-(3-methylphenyl)-1,3-thiazole合成路线

1.合成路线

791053-96-8

631-58-3

38%

365428-57-5

参考文献

Miwatashi, Seiji; Arikawa, Yasuyoshi; Kotani, Etsuo; Miyamoto, Maki; Naruo, Ken-Ichi; Kimura, Hiroyuki; Tanaka, Toshimasa; Asahi, Satoru; Ohkawa, Shigenori Journal of Medicinal Chemistry, 2005 , vol. 48, # 19 p. 5966 - 5979

2.合成路线

631-58-3

365428-13-3

144-55-8

37%

365428-57-5

参考文献

Ohkawa, Shigenori; Naruo, Ken-ichi; Miwatashi, Seiji; Kimura, Hiroyuki Patent: US2004/53973 A1, 2004 ; US 20040053973 A1

3.合成路线

631-58-3

365428-13-3

36%

365428-57-5

参考文献

Takeda Chemical Industries, Ltd. Patent: EP1364949 A1, 2003 ; Location in patent: Page/Page column 83 ;
2-ethyl-5-(2-fluoropyridin-4-yl)-4-(3-methylphenyl)-1,3-thiazole上下游产品

上游产品

365428-13-3

631-58-3
硫代丙酰胺

791053-96-8

21384-43-0

下游产品

365428-57-5

上游百科 硫代丙酰胺 2-氟-4-甲基吡啶