6-chloro-1-ethyl-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid - CAS号 67681-84-9 - 摩贝百科

: 6-chloro-1-ethyl-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

CAS号：
67681-84-9

分子式：C16H18ClN3O3

6-chloro-1-ethyl-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid基本信息

中文全称

中文别名

英文名称

6-chloro-1-ethyl-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

英文别名

6-chloro-1-ethyl-4-oxo-7-piperazinyl-1,4-dihydro-quinoline-3-carboxylic acid;6-chloro-1-ethyl-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid;

PSA

74.57000

LogP

2.17640
6-chloro-1-ethyl-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid物化性质

折射率

1.615

闪点

308.4ºC

密度

1.369g/cm3

沸点

586.4ºC at 760 mmHg
6-chloro-1-ethyl-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid图谱

核磁图谱

1H NMR : Predict

13C NMR : Predict
6-chloro-1-ethyl-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid合成路线

1.合成路线

110-85-0

67681-88-3

64%

67681-84-9

参考文献

Koga, Hiroshi; Itoh, Akira; Murayama, Satoshi; Suzue, Seigo; Irikura, Tsutomu Journal of Medicinal Chemistry, 1980 , vol. 23, # 12 p. 1358 - 1363

2.合成路线

110-85-0

109-86-4

67681-88-3

67681-84-9

参考文献

Laboratorie Roger Bellon; Dainippon Pharmaceutical Patent: US4292317 A1, 1981 ; US 4292317 A
6-chloro-1-ethyl-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid上下游产品

上游产品

110-85-0
哌嗪

67681-88-3

109-86-4
乙二醇甲醚

下游产品

67681-84-9