deltaN-苄氧羰基阿利吉仑

deltaN-苄氧羰基阿利吉仑基本信息

中文全称

deltaN-苄氧羰基阿利吉仑

中文别名

英文名称

benzyl N-[(3S,5S,6S,8S)-8-[(3-amino-2,2-dimethyl-3-oxopropyl)carbamoyl]-6-hydroxy-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-2,9-dimethyldecan-5-yl]carbamate

英文别名

(|AS,|AS,|AS,zS)-|A-(Benzyloxycarbonyl)amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-|A-hydroxy-4-methoxy-3-(3-methoxypropoxy)-|A,z-bis(1-methylethyl)benzeneoctanamide;|AN-Benzyloxycarbonyl Rasilez;|AN-Benzyloxycarbonyl Tekturna;benzyl (3S,5S,6S,8S)-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-8-((3-amino-2,2-dimethyl-3-oxopropyl)carbamoyl)-6-hydroxy-2,9-dimethyldecan-5-ylcarbamate;(1S,2S,4S)-4-(2-carbamoyl-2-methylpropylcarbamoyl)-2-hydroxy-1-{(S)-2-[4-methoxy-3-(3-methoxypropoxy)benzyl]-3-methylbutyl}-5-methylhexylcarbamic acid benzyl ester;|AN-Benzyloxycarbonyl Aliskiren;N-[(1S,2S,4S)-4-[[(3-Amino-2,2-dimethyl-3-oxopropyl)amino]carbonyl]-2-hydroxy-1-[(2S)-2-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-3-methylbutyl]-5-methylhexyl]carbamic Acid Phenylmethyl Ester;benzyl ((3S,5S,6S,8S)-8-((3-amino-2,2-dimethyl-3-oxopropyl)carbamoyl)-6-hydroxy-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-2,9-dimethyldecan-5-yl)carbamate;

PSA

166.41000

LogP

7.45560
deltaN-苄氧羰基阿利吉仑图谱

核磁图谱

1H NMR : Predict

13C NMR : Predict
deltaN-苄氧羰基阿利吉仑合成路线

1.合成路线

1376616-31-7

75315-63-8

99%

1236549-06-6

参考文献

Craighead, Mark; Palin, Ronald; Murray, Neil; Lindsay, Derek Patent: US2013/225594 A1, 2013 ; Location in patent: Paragraph 0494; 0494 ;

2.合成路线

13139-17-8

1376616-31-7

99%

1236549-06-6

参考文献

REDX PHARMA LIMITED; CRAIGHEAD, Mark; PALIN, Ronald; MURRAY, Neil; LINDSAY, Derek Patent: WO2012/63085 A2, 2012 ; Location in patent: Page/Page column 126-127 ; WO 2012/063085 A2

3.合成路线

324763-51-1

1236549-00-0

86%

1236549-06-6

参考文献

CHEMO IBERICA, S. A.; CARCONE, Luca; MAGRONE, Domenico; BARRECA, Giuseppe; RASPARINI, Marcello; LI MING, Huan Patent: WO2013/14191 A1, 2013 ; Location in patent: Page/Page column 17; 18 ;
deltaN-苄氧羰基阿利吉仑上下游产品

上游产品

1376616-31-7

1236549-00-0

1236549-06-6
deltaN-苄氧羰基阿利吉仑

1322077-30-4
(R)-4-(4-甲氧基-3-(3-甲氧基丙氧基)苄基)-5-甲基己酸

下游产品

1236549-06-6
deltaN-苄氧羰基阿利吉仑

173334-57-1
阿利吉仑

173334-58-2
阿利吉仑半富马酸盐

上游百科 3-氨基-2,2-二甲基丙酰胺苯甲氧羰酰琥珀酰亚胺 (R)-3-(3-甲基丁酰)-4-苄基-2-恶唑烷酮 4-溴-1-甲氧基-2-(3-甲氧基丙氧基)苯 4-[(2R)-2-(氯甲基)-3-甲基丁基]-1-甲氧基-2-(3-甲氧基丙氧基)苯
下游百科 阿利吉仑阿利吉仑半富马酸盐

1236549-06-6

deltaN-苄氧羰基阿利吉仑基本信息

deltaN-苄氧羰基阿利吉仑图谱

deltaN-苄氧羰基阿利吉仑合成路线

1.合成路线

1376616-31-7

75315-63-8

1236549-06-6

2.合成路线

13139-17-8

1376616-31-7

1236549-06-6

3.合成路线

324763-51-1

1236549-00-0

1236549-06-6

deltaN-苄氧羰基阿利吉仑上下游产品

上游产品

下游产品

上游百科

下游百科