tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate

tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate基本信息

中文全称

中文别名

英文名称

tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate

英文别名

1,1-dimethylethyl 4-[4-amino-3-(methyloxy)phenyl]-1-piperidine carboxylate;1-Piperidinecarboxylic acid,4-(4-amino-3-methoxyphenyl)-,1,1-dimethylethyl ester;D-1291;

PSA

64.79000

LogP

3.91100
tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate图谱

核磁图谱

13C NMR : Predict

1H NMR : Predict
tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate合成路线

1.合成路线

6627-53-8

375853-82-0

80%

1089280-53-4

参考文献

Kuntz, Kevin; Uehling, David Edward; Waterson, Alex Gregory; Emmitte, Kyle Allen; Stevens, Kirk; Shotwell, John Brad; Smith, Stephon Cornell; Nailor, Kristen E.; Salovich, James M.; Wilson, Brian John; Cheung, Mui; Mook, Robert Anthony; Baum, Erich W.; Moorthy, Ganesh Patent: US2008/300242 A1, 2008 ; Location in patent: Page/Page column 109 ; US 20080300242 A1

2.合成路线

1233145-65-7

10%

1089280-53-4

参考文献

SANOFI Patent: US2012/277220 A1, 2012 ; Location in patent: Page/Page column 17 ;

3.合成路线

6627-53-8

1089280-53-4

参考文献

Mesaros, Eugen F.; Thieu, Tho V.; Wells, Gregory J.; Zificsak, Craig A.; Wagner, Jason C.; Breslin, Henry J.; Tripathy, Rabindranath; Diebold, James L.; McHugh, Robert J.; Wohler, Ashley T.; Quail, Matthew R.; Wan, Weihua; Lu, Lihui; Huang, Zeqi; Albom, Mark S.; Angeles, Thelma S.; Wells-Knecht, Kevin J.; Aimone, Lisa D.; Cheng, Mangeng; Ator, Mark A.; Ott, Gregory R.; Dorsey, Bruce D. Journal of Medicinal Chemistry, 2012 , vol. 55, # 1 p. 115 - 125
tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate上下游产品

上游产品

1246533-06-1

103966-66-1
5-溴-2-硝基苯甲醚

59557-91-4
2-甲氧基-4-溴苯胺

6627-53-8
5-氯-2-硝基苯甲醚

下游产品

1089280-53-4

上游百科 5-氯-2-硝基苯甲醚 2-甲氧基-4-溴苯胺 1,2,3,6-四氢吡啶-4-硼酸频那醇酯 2-氟-4-溴硝基苯 5-溴-2-硝基苯甲醚

1089280-53-4

tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate基本信息

tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate图谱

tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate合成路线

1.合成路线

6627-53-8

375853-82-0

1089280-53-4

2.合成路线

1233145-65-7

1089280-53-4

3.合成路线

6627-53-8

1089280-53-4

tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate上下游产品

上游产品

下游产品

上游百科