2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide

2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyr...基本信息

中文全称

中文别名

英文名称

2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyridinyl]ethyl}acetamide

英文别名

PSA

80.49000

LogP

5.04830
2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyr...图谱

核磁图谱

1H NMR : Predict
2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyr...合成路线

1.合成路线

95-58-9

1146395-43-8

75%

1146395-46-1

参考文献

MERCK and CO., INC. Patent: WO2009/54984 A1, 2009 ; Location in patent: Page/Page column 43-44 ;

2.合成路线

953780-33-1

1240606-62-5

1146395-46-1

参考文献

Yang, Zhi-Qiang; Schlegel, Kelly-Ann S.; Shu, Youheng; Reger, Thomas S.; Cube, Rowena; Mattern, Christa; Coleman, Paul J.; Small, Jim; Hartman, George D.; Ballard, Jeanine; Tang, Cuyue; Kuo, Yuhsin; Prueksaritanont, Thomayant; Nuss, Cindy E.; Doran, Scott; Fox, Steve V.; Garson, Susan L.; Li, Yuxing; Kraus, Richard L.; Uebele, Victor N.; Taylor, Adekemi B.; Zeng, Wei; Fang, Wei; Chavez-Eng, Cynthia; Troyer, Matthew D.; Luk, Julie Ann; Laethem, Tine; Cook, William O.; Renger, John J.; Barrow, James C. ACS Medicinal Chemistry Letters, 2010 , vol. 1, # 9 p. 504 - 509
2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyr...上下游产品

上游产品

1240606-62-5

953780-33-1
(R)-1-(5-(2,2,2-三氟乙氧基)吡啶-2-基)乙胺

1146395-43-8

95-58-9
2-氯-3-甲基吡嗪

下游产品

1146395-46-1

上游百科 2-氯-3-甲基吡嗪 (R)-1-(5-(2,2,2-三氟乙氧基)吡啶-2-基)乙胺

1146395-46-1

2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyr...基本信息

2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyr...图谱

2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyr...合成路线

1.合成路线

95-58-9

1146395-43-8

1146395-46-1

2.合成路线

953780-33-1

1240606-62-5

1146395-46-1

2-[4-(3-Methyl-2-pyrazinyl)phenyl]-N-{(1R)-1-[5-(2,2,2-trifluoroe thoxy)-2-pyr...上下游产品

上游产品

下游产品

上游百科