2-chloro-5,11-dimethyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one - CAS号 1234479-75-4 - 摩贝百科

: 2-chloro-5,11-dimethyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one

CAS号：
1234479-75-4

分子式：C13H11ClN4O

2-chloro-5,11-dimethyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one基本信息

中文全称

中文别名

英文名称

2-chloro-5,11-dimethyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one

英文别名

PSA

52.71000

LogP

2.03580
2-chloro-5,11-dimethyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one图谱

核磁图谱

13C NMR : Predict

1H NMR : Predict
2-chloro-5,11-dimethyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one合成路线

1.合成路线

66427-86-9

74-88-4

78%

1234479-75-4

参考文献

DANA FARBER CANCER INSTITUTE; GRAY, Nathanael, S.; DENG, Xianming; KWIATKOWSKI, Nicholas, Paul Patent: WO2010/80712 A2, 2010 ; Location in patent: Page/Page column 53 ; WO 2010/080712 A2

2.合成路线

35472-56-1

1234479-75-4

参考文献

Deng, Xianming; Yang, Qingkai; Kwiatkowski, Nicholas; Sim, Taebo; McDermott, Ultan; Settleman, Jeffrey E.; Lee, Jiing-Dwan; Gray, Nathanael S. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 3 p. 195 - 200

3.合成路线

1234479-74-3

1234479-75-4

参考文献

ACS Medicinal Chemistry Letters, , vol. 2, # 3 p. 195 - 200
2-chloro-5,11-dimethyl-pyrimido[4,5-b][1,4]benzodiazepin-6-one上下游产品

上游产品

66427-86-9

1234479-74-3

122833-04-9
2-甲氧基-4-(4-甲基哌嗪-1-基)苯胺

1234479-75-4

下游产品

1234479-76-5

1234479-75-4

上游百科 2-(甲基氨基)苯甲酸乙酯 2-chloro-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
下游百科 2-{[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-5,11-dimeth yl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one