2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydro-6-quinazolinyl]methyl}(2-propyn-1-yl)amino]benzoate<wbr

2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydr...基本信息

中文全称

中文别名

英文名称

2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydro-6-quinazolinyl]methyl}(2-propyn-1-yl)amino]benzoate<wbr

英文别名

tert-butyl 4-[1-(3-chloro-4-fluorophenyl)-2-hydroxyethyl]piperazine-1-carboxylate;tert-butyl 4-[N-[2-acetoxymethyl-7-chloro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylmethyl]-N-(prop-2-ynyl)amino]benzoate;tert-butyl 4-[2-amino-4-(methoxycarbonyl)phenyl]piperazine-1-carboxylate;tert-butyl 4-[1-(phenylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine-5-yl]-1H-pyrazole-1-carboxylate;

PSA

90.73000

LogP

4.24510
2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydr...图谱

核磁图谱

1H NMR : Predict

13C NMR : Predict
2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydr...合成路线

1.合成路线

112888-76-3

289686-86-8

73%

289686-87-9

参考文献

Cancer Research Technology Limited Patent: US6699861 B1, 2004 ; Location in patent: Page column 17 ; US 6699861 B1

2.合成路线

289686-85-7

289686-87-9

参考文献

Bavetsias; Skelton; Yafai; Mitchell; Wilson; Allan; Jackman Journal of Medicinal Chemistry, 2002 , vol. 45, # 17 p. 3692 - 3702

3.合成路线

289686-84-6

289686-87-9

参考文献

Bavetsias; Skelton; Yafai; Mitchell; Wilson; Allan; Jackman Journal of Medicinal Chemistry, 2002 , vol. 45, # 17 p. 3692 - 3702
2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydr...上下游产品

上游产品

458533-71-6

289686-84-6

155184-81-9
2-氨基-4-氯-5-甲基苯甲酸

289686-87-9

下游产品

289686-87-9

289715-28-2
CB 300919; 4-[[[7-氯-3,4-二氢-3-甲基-2-[(4-甲基-1-哌嗪基)甲基]-4-氧代-6-喹唑啉基]甲基]-2-丙炔-1-基氨基]-N-(3-吡啶基甲基)苯甲酰胺

上游百科 3-氯-4-甲基苯胺 2-氨基-4-氯-5-甲基苯甲腈 3-氟-4-甲基乙酰苯胺 2-氨基-4-氯-5-甲基苯甲酸 2-溴-5-氯-4-甲基苯胺 4-(2-丙炔氨基)苯甲酸叔丁酯 N-乙酰基-2-溴-5-氯-4-甲基苯胺
下游百科 CB 300919; 4-[[[7-氯-3,4-二氢-3-甲基-2-[(4-甲基-1-哌嗪基)甲基]-4-氧代-6-喹唑啉基]甲基]-2-丙炔-1-基氨基]-N-(3-吡啶基甲基)苯甲酰胺

289686-87-9

2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydr...基本信息

2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydr...图谱

2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydr...合成路线

1.合成路线

112888-76-3

289686-86-8

289686-87-9

2.合成路线

289686-85-7

289686-87-9

3.合成路线

289686-84-6

289686-87-9

2-Methyl-2-propanyl 4-[{[2-(acetoxymethyl)-7-chloro-3-methyl-4-ox o-3,4-dihydr...上下游产品

上游产品

下游产品

上游百科

下游百科