1,2,3,6-四氢吡啶-4-硼酸频那醇酯

1,2,3,6-四氢吡啶-4-硼酸频那醇酯基本信息

中文全称

1,2,3,6-四氢吡啶-4-硼酸频那醇酯

中文别名

1,2,3,6-四氢吡啶-4-硼酸频哪醇酯;

英文名称

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine

英文别名

(N-tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester;Pyridine,1,2,3,6-tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl);TERT-BUTYL 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,6-DIHYDRO-1(2H)-PYRIDINECARBOXYLATE;N-boc-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine;tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydro-1-pyridinecarboxylate;4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester;1,2,3,6-Tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;1,2,3,6-TETRAHYDROPYRIDINE-4-YL-BORONIC ACID PINACOL ESTER;tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate;

PSA

30.49000

LogP

1.86630
1,2,3,6-四氢吡啶-4-硼酸频那醇酯物化性质

折射率

1.477

闪点

103ºC

密度

0.99

沸点

246ºC
1,2,3,6-四氢吡啶-4-硼酸频那醇酯安全信息

海关编码

2934999090
1,2,3,6-四氢吡啶-4-硼酸频那醇酯图谱

核磁图谱

13C NMR : Predict

1H NMR : Predict
1,2,3,6-四氢吡啶-4-硼酸频那醇酯合成路线

1.合成路线

138647-49-1

73183-34-3

98%

375853-82-0

参考文献

SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE; DUKE UNIVERSITY; PINKERTON, Anthony; MALONEY, Patrick; HERSHBERGER, Paul; PEDDIBHOTLA, Satyamaheshwar; HEDRICK, Michael; BARAK, Lawrence; CARON, Marc Patent: WO2014/100501 A1, 2014 ; Location in patent: Paragraph 00727; 00728 ;

2.合成路线

79099-07-3

73183-34-3

97%

375853-82-0

参考文献

Yoshizumi, Takashi; Takahashi, Hirobumi; Miyazoe, Hiroshi; Sugimoto, Yuichi; Tsujita, Tomohiro; Kato, Tetsuya; Ito, Hirokatsu; Kawamoto, Hiroshi; Hirayama, Mioko; Ichikawa, Daisuke; Azuma-Kanoh, Tomoko; Ozaki, Satoshi; Shibata, Yoshihiro; Tani, Takeshi; Chiba, Masato; Ishii, Yasuyuki; Okuda, Shoki; Tadano, Kiyoshi; Fukuroda, Takahiro; Okamoto, Osamu; Ohta, Hisashi Journal of Medicinal Chemistry, 2008 , vol. 51, # 13 p. 4021 - 4029

3.合成路线

10221-56-4

138647-49-1

79%

375853-82-0

参考文献

Kim, Eunkyung; Park, Chan Sun; Han, Taedong; Bae, Myung-Ho; Chong, Wonee; Lee, Choong Hyun; Shin, Young Ah; Ahn, Byung-Nak; Kim, Mi Kyung; Shin, Chang Yell; Son, Moon Ho; Kim, Jin Kwan; Moon, Ho Sang; Shim, Hyun Joo; Kim, Eun Jung; Kim, Soon Hoe; Lim, Joong In; Lee, Chun Ho Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 18 p. 4993 - 4996
1,2,3,6-四氢吡啶-4-硼酸频那醇酯海关数据

中国海关编码

2934999090

概述

2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

申报要素

品名, 成分含量, 用途
1,2,3,6-四氢吡啶-4-硼酸频那醇酯上下游产品

上游产品

875798-37-1

680192-98-7

103966-66-1
5-溴-2-硝基苯甲醚

10221-56-4

下游产品

1048970-17-7
1-N-叔丁氧羰基哌啶-4-硼酸频哪醇酯

1227068-67-8
1-乙酰基-5,6-二氢-2H-吡啶-4-硼酸频那醇酯

876343-86-1
4-(5-溴-4-氯-1H-吡咯并[2,3-B]吡啶-2-基)-3,6-二氢-1(2H)-吡啶羧酸 1,1-二甲基乙酯

1158767-08-8
4-(1H-吲唑-5-基)哌啶-1-羧酸叔丁酯

上游百科 频哪醇频哪醇硼烷 4-氧代哌啶酮盐酸盐二碳酸二叔丁酯联硼酸频那醇酯 3,6-二氢-4-[[(三氟甲基)磺酰]氧基]-1(2H)-吡啶甲酸叔丁酯
下游百科 4-(3-羟苯基)哌啶 4-(4-氟苯基)呱碇 N-BOC-1,2,3,6-四氢吡啶 [1-(叔丁氧基羰基)-1,2,3,6-四氢吡啶-4-基]硼酸 1,2,3,6-四氢-4-(4,4,5,5-四甲基-1,3,2- 二噁硼烷-2-基)吡啶盐酸盐 1-乙酰基-5,6-二氢-2H-吡啶-4-硼酸频那醇酯 4-(4-氨基苯基)哌啶-1-甲酸叔丁酯 4-(6-氨基吡啶-3-基)哌啶-1-羧酸叔丁酯 tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate 1-N-叔丁氧羰基哌啶-4-硼酸频哪醇酯

375853-82-0

1,2,3,6-四氢吡啶-4-硼酸频那醇酯基本信息

1,2,3,6-四氢吡啶-4-硼酸频那醇酯物化性质

1,2,3,6-四氢吡啶-4-硼酸频那醇酯安全信息

1,2,3,6-四氢吡啶-4-硼酸频那醇酯图谱

1,2,3,6-四氢吡啶-4-硼酸频那醇酯合成路线

1.合成路线

138647-49-1

73183-34-3

375853-82-0

2.合成路线

79099-07-3

73183-34-3

375853-82-0

3.合成路线

10221-56-4

138647-49-1

375853-82-0

1,2,3,6-四氢吡啶-4-硼酸频那醇酯海关数据

1,2,3,6-四氢吡啶-4-硼酸频那醇酯上下游产品

上游产品

下游产品

上游百科

下游百科