(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]butanoyl]amino]butanoyl]amino]butanoyl]amino]pentanedioic acid

(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diam...基本信息

中文全称

中文别名

英文名称

(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]butanoyl]amino]butanoyl]amino]butanoyl]amino]pentanedioic acid

英文别名

methotrexate triglutamate;4-NH2-10-CH3-folyldiglutamate;MTX triglutamate;L-Glutamic acid,N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-g-glutamyl;4-NH2-10-CH3-folyltriglutamate;MTX diglutamate;methotrexate tetraglutamate;4-NH2-10-CH3-folyltetraglutamate;4-amino-4-deoxy-N10-methylpteroyltetraglutamate;4-Amino-4-deoxy-N10-methylpteroylglutamyl-g-glutamate;4-amino-10-methylpteroyldiglutamate;MTX tetraglutamate;

PSA

409.74000

LogP

1.04320
(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diam...物化性质

折射率

1.669

密度

1.541g/cm3
(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diam...合成路线

1.合成路线

52853-40-4

83816-96-0

80%

73610-81-8

参考文献

Piper, James R.; McCaleb, George S.; Montgomery, John A. Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 291 - 294

2.合成路线

124126-68-7

73610-81-8

参考文献

Abraham; Nair; Kisliuk; Gaumont; Galivan Journal of Medicinal Chemistry, 1990 , vol. 33, # 2 p. 711 - 717

3.合成路线

84793-07-7

73610-81-8

参考文献

Abraham; Nair; Kisliuk; Gaumont; Galivan Journal of Medicinal Chemistry, 1990 , vol. 33, # 2 p. 711 - 717
(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diam...上下游产品

上游产品

56892-71-8

83816-92-6

84793-07-7
芴甲氧羰基-L-谷氨酸 1-叔丁酯

52853-40-4
6-溴乙基-喋啶-2,4-二胺

下游产品

73610-81-8

上游百科 L-谷氨酸 1-叔丁酯 4-[N-(2,4-二氨基-6-蝶啶甲基)-N-甲氨基]苯甲酸半盐酸盐n水 6-溴乙基-喋啶-2,4-二胺 N-叔丁氧羰基-L-谷氨酸 1-苄酯芴甲氧羰基-L-谷氨酸 1-叔丁酯

73610-81-8

(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diam...基本信息

(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diam...物化性质

(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diam...合成路线

1.合成路线

52853-40-4

83816-96-0

73610-81-8

2.合成路线

124126-68-7

73610-81-8

3.合成路线

84793-07-7

73610-81-8

(2S)-2-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[(4S)-4-carboxy-4-[[4-[(2,4-diam...上下游产品

上游产品

下游产品

上游百科