2-chloro-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one - CAS号 66427-86-9 - 摩贝百科

: 2-chloro-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

CAS号：
66427-86-9

分子式：C12H9ClN4O

2-chloro-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one基本信息

中文全称

中文别名

英文名称

2-chloro-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

英文别名

6H-Pyrimido(4,5-b)(1,4)benzodiazepin-6-one,2-chloro-5,11-dihydro-11-methyl;2-Chloro-11-methylpyrimido-<4,5-b><1,4>-benzodiazepin-6(5H)-on;2-chloro-11-methyl-5,11-dihydro-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one;2-Chloro-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;

PSA

63.57000

LogP

2.02540
2-chloro-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one物化性质

折射率

1.636

闪点

195.5ºC

密度

1.403g/cm3

沸点

399.7ºC at 760 mmHg
2-chloro-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one图谱

核磁图谱

13C NMR : Predict

1H NMR : Predict
2-chloro-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one合成路线

1.合成路线

35472-56-1

66427-86-9

参考文献

Deng, Xianming; Yang, Qingkai; Kwiatkowski, Nicholas; Sim, Taebo; McDermott, Ultan; Settleman, Jeffrey E.; Lee, Jiing-Dwan; Gray, Nathanael S. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 3 p. 195 - 200
2-chloro-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one上下游产品

上游产品

66427-86-9

35472-56-1
2-(甲基氨基)苯甲酸乙酯

74-88-4
甲基碘

下游产品

66427-86-9

1234479-76-5

1234479-75-4

上游百科 2-(甲基氨基)苯甲酸乙酯
下游百科 2-{[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino}-5,11-dimeth yl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one