2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol

2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol基本信息

中文全称

中文别名

英文名称

2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol

英文别名

(+)-Colchicin;(R)-7-chloro-4-{[1'-(hydroxymethyl)-4'-(diethylamino)butyl]amino}quinoline;COLCHICINE,(+);Acetamide,N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-,(R);(R)-7-Acetylamino-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-on;Lopac-C-9754;Colchicine,(R)-Isomer;

PSA

48.39000

LogP

3.85600
2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol物化性质

闪点

266.4ºC

密度

1.176g/cm3

沸点

516.9ºC at 760mmHg
2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol图谱

核磁图谱

13C NMR : Predict

1H NMR : Predict
2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol合成路线

1.合成路线

86-98-6

77529-88-5

56%

77529-96-5

参考文献

Witiak, Donald T.; Grattan, David A.; Heaslip, Richard J.; Rahwan, Ralf G. Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 712 - 717

2.合成路线

77529-87-4

77529-96-5

参考文献

Witiak, Donald T.; Grattan, David A.; Heaslip, Richard J.; Rahwan, Ralf G. Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 712 - 717

3.合成路线

77529-84-1

77529-96-5

参考文献

Witiak, Donald T.; Grattan, David A.; Heaslip, Richard J.; Rahwan, Ralf G. Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 712 - 717
2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol上下游产品

上游产品

77529-88-5

86-98-6
4,7-二氯喹林

77529-84-1

77529-87-4
N,N-二乙基-(R)-谷氨酰胺盐酸盐

下游产品

77529-96-5

上游百科 4,7-二氯喹林 BOC-D-谷氨酸

77529-96-5

2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol基本信息

2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol物化性质

2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol图谱

2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol合成路线

1.合成路线

86-98-6

77529-88-5

77529-96-5

2.合成路线

77529-87-4

77529-96-5

3.合成路线

77529-84-1

77529-96-5

2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol上下游产品

上游产品

下游产品

上游百科